Search results for "Type III Procollagen"

showing 2 items of 2 documents

Serum hyaluronate and type III procollagen aminoterminal propeptide concentration in chronic liver disease. Relationship to cirrhosis and disease act…

1991

. To analyse the relationship between the presence of liver cirrhosis and hepatic inflammation and the serum concentrations of the aminoterminal propeptide of procollagen type III (P-III-NP) and of hyaluronic acid (HA) in chronic liver disease, we measured P-III-NP and HA concentrations in paired serum samples from 133 patients with various chronic liver diseases, from 22 patients with acute hepatitis and from 50 healthy age-matched controls. In 24 (of the 133) patients with autoimmune chronic liver disease, follow-up determination was performed during therapeutic treatment with immunosuppressive drugs. Compared with controls P-III-NP concentrations (medians) were significantly elevated in …

AdultLiver CirrhosisMalemedicine.medical_specialtyCirrhosisClinical BiochemistryChronic liver diseaseBiochemistryGastroenterologyAutoimmune DiseasesHepatitisDisease activityDiagnosis Differentialchemistry.chemical_compoundInternal medicineHyaluronic acidmedicineHumansHyaluronic AcidProtein precursorHepatitis ChronicHepatitisChronic Activebusiness.industryLiver DiseasesGeneral MedicineMiddle Agedmedicine.diseasePeptide FragmentsType III ProcollagenchemistryImmunologyFemalebusinessBiomarkersProcollagenEuropean journal of clinical investigation
researchProduct

Combined evaluation of resting IGF-I, N-terminal propeptide of type III procollagen (PIIINP) and C-terminal cross-linked telopeptide of type I collag…

2004

To verify whether combined measurements of GH-dependent parameters might be useful in detecting exogenous recombinant GH (rGH) administration in male athletes from different disciplines.Sixty-six athletes (control group) were sampled for the evaluation of resting IGF-I, N-terminal propeptide of type III procollagen (PIIINP) and telopeptide type I collagen (ICTP). Cut-off values (mean + 2 SD) for IGF-I, PIIINP and ICTP were calculated and arbitrary scores (1.5, 2.0) were assigned to abnormal parameters. By using the sum of individual parameter scores, positive (or = 3) or negative (3) scores were obtained. In addition, a subgroup of six athletes was treated for 3 weeks with rGH (0.09 IU/kg b…

AdultMalemedicine.medical_specialtyAdolescentEndocrinology Diabetes and MetabolismRhgh treatmentSensitivity and SpecificityCollagen Type IEndocrinologyN-terminal telopeptidePreliminary reportInternal medicinemedicineHumansInsulin-Like Growth Factor IDoping in Sportsbiologybusiness.industryAthletesN terminal propeptidebiology.organism_classificationPeptide FragmentsType III ProcollagenProcollagen peptidaseEndocrinologyCase-Control StudiesGrowth HormonebusinessPeptidesType I collagenBiomarkersProcollagenSportsClinical endocrinology
researchProduct